spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online May 10, 2006
doi: 10.1242/10.1242/jcs.03008

Journal of Cell Science 119, 1977-1984 (2006)
Published by The Company of Biologists 2006
This Article
Right arrow Summary Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by von Mikecz, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by von Mikecz, A.

The nuclear ubiquitin-proteasome system

Anna von Mikecz

Institut für umweltmedizinische Forschung, Heinrich-Heine-Universität Düsseldorf, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany


Figure 1
View larger version (45K):

[in a new window]
  		Fig. 1. Function and localization of nuclear UPS components. Micrographs on the right show confocal immunofluorescence of HEp-2 cells with antibodies against components of the UPS: rabbit polyclonal anti-ubiquitin (Ub FL-76; red), mouse monoclonal anti-20S proteasome core subunits (20S core; gray), mouse monoclonal anti-19S regulator (19S Rpt6, purple) and rabbit anti-ubiquitin-conjugating enzyme E2 (UbcH6, green). Micrographs in the left show corresponding differential interference contrast (DIC) images. Ub, ubiquitin; 19S-20S-19S, 26S proteasome; 19S, 19S regulator complex; E1, ubiquitin-activating enzyme; E2, ubiquitin-conjugating enzyme; E3, ubiquitin ligase. Bar, 5 µm.

 




© The Company of Biologists Ltd 2006