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Quarterly Journal of Microscopical Science, Vol s3-105, 227-230, Copyright © 1964 by Company of Biologists

The Effect of Certain Fixatives on Particles of a Globular Protein: An Electron-Microscopical Study

K. DEUTSCH 1, E. FISCHER 1, and W. KRAUSE 1

1 Department of Electron Microscopy, University of Greifswald, East Germany

Particles (regarded as molecules) of bovine serum albumin have been studied by electron microscopy both in the untreated state and after fixation with osmium tetroxide, formaldehyde, and potassium permanganate. All three fixatives, especially potassium permanganate, increased the density of the particles considerably.







© The Company of Biologists Ltd 1964