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Journal of Cell Science, Vol 9, 823-833, Copyright © 1971 by Company of Biologists

Revised on May 12, 1971

SIALIC ACID AND CELL AGGREGATION

P. MCQUIDDY 1 and J. LILIEN 1

1 Department of Zoology, University of Wisconsin Madison, Wisconsin 53706, U.S.A.

Chick embryo neural retina cells from 7-, 10- and 14-day embryos and muscle cells from 9-day embryos, dissociated mechanically or with trypsin, reaggregate at the same initial rate whether treated before and during aggregation with active or inactive N-acetyl neuraminidase. N-acetyl neuraminidase treatment also has no effect on the size or number of aggregates formed over 24 or 48 h of aggregation. It was also found that the amount of trypsin used to dissociate the tissue into single cells alters the initial rate of aggregation but has no effect on the size or number of aggregates formed over a 24-h period.

Revised on May 12, 1971






© The Company of Biologists Ltd 1971