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Journal of Cell Science, Vol 7, 1-3, Copyright © 1970 by Company of Biologists

Submitted on November 8, 1969

Species Specificity of an Enzyme Determined by an Erythrocyte Nucleus in an Interspecific Hybrid Cell

P. R. COOK 1

1 Sir William Dunn School of Pathology, University of Oxford, England

When a chick erythrocyte nucleus is introduced into the cytoplasm of a mutant mouse cell lacking inosinic acid pyrophosphorylase, synthesis of the enzyme is induced. The enzyme induced in this way has the characteristics of chick, not mouse, inosinic acid pyrophosphorylase.

Submitted on November 8, 1969






© The Company of Biologists Ltd 1970