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Journal of Cell Science, Vol 41, Issue 1 125-133, Copyright © 1980 by Company of Biologists

JOURNAL ARTICLES

Red blood cell adhesion. I. Determination of the ionic conditions for adhesion to an oil-water interface

I Todd and D Gingell

We have examined the adhesion of glutaraldehyde-treated human red blood cells to a clean liquid hydrocarbon interface as a function of sodium chloride concentration. Cells adhere reversibly to the interface over a wide range of concentrations but fail to do so below about 0.1 mM. Adherent cells do not alter the tension of the oil/water interface. These results show that cells can adhere by physical forces in special situations without biochemical interactions. The data provide a basis for calculating the size of the physical forces.




© The Company of Biologists Ltd 1980