spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rutz, R.
Right arrow Articles by Lilien, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rutz, R.
Right arrow Articles by Lilien, J.

Journal of Cell Science, Vol 36, Issue 1 323-342, Copyright © 1979 by Company of Biologists

JOURNAL ARTICLES

Functional characterization of an adhesive component from the embryonic chick neural retina

R Rutz and J Lilien

We have developed a quantitative assay for tissue-specific adhesive components which is based on the agglutination of glutaraldehyde-fixed cells. At least 2 components are required for fixed-cell agglutination: a cell-surface ligand which is obtained from tissue culture-conditioned medium, and a soluble 'agglutinin' which accumulates in conditioned medium from monolayer cultures. Our results suggest that the surface-binding ligand and the agglutinin interact directly, resulting in tissue-specific agglutination of cells. The agglutination reaction exhibits divalent cation, temperature, and pH dependence. Several models of cell adhesion are described; the simplest of these which can account for the data is a multicomponent model in which the 2 adhesive components have structural roles.


This article has been cited by other articles:


Home page
 ScienceHome page
M Nirenberg, S Wilson, H Higashida, A Rotter, K Krueger, N Busis, R Ray, J. Kenimer, and M Adler
Modulation of synapse formation by cyclic adenosine monophosphate
Science, November 18, 1983; 222(4625): 794 - 799.
[Abstract] [PDF]


© The Company of Biologists Ltd 1979