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Journal of Cell Science, Vol 32, Issue 1 185-195, Copyright © 1978 by Company of Biologists

JOURNAL ARTICLES

New staining method for the detection of sister-chromatid exchanges in BrdU-labelled chromosomes

P Alves and J Jonasson

A direct Giemsa technique is described for the selective staining of Brd-U-substituted chromatin. It can advantageously be used for sister-chromatid exchange analysis and for the detailed cytological study of the mouse kinetochores. Presumptive inversions within the centromeric region of chromosomes 4 and 18 in the C57Black/6J mouse are described.


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© The Company of Biologists Ltd 1978