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Journal of Cell Science, Vol 25, Issue 1 355-366, Copyright © 1977 by Company of Biologists

JOURNAL ARTICLES

Glycosyltrasferase activity in developing sea-urchin embryos

IM Evans and HB Bosmann

The developmental course of activity changes of 4 endogenous membrane glycosyltransferases: UDP-glucose : glycosyltrasferase, UDP-galactose : glycosyltransferase, GDP-mannose: glycosyltransferase, and UD-PN-acetylglucosamine : glycosyltransferase was determined in various stages of developing sea-urchin embryos from unfertilized eggs up to the 16-cell stage. The results show that there is a 2-fold increase in glycosyltransferase activity after fertilization. These results are discussed in relation to the postulated role of glycosyltransferases in mediating adhesion, recognition, and agglutination of cells and embryos.




© The Company of Biologists Ltd 1977