Fig. 6. (A) Representative trajectories of DC-SIGN undergoing directed (red) or non-directed (green) motion relative to the cell edge (gray line). The red arrow denotes overall direction of DC-SIGN displacement for the directed motion trajectory. All trajectories were obtained from live MDDCs stained with anti-DC-SIGN F(ab). Scale bar, 1 µm. (B) Mean square displacement versus time for DC-SIGN trajectories exhibiting directed motion (n=4).