Fig. 5. Spatial arrangement of ERES in vivo. The distribution of (normalized) next-neighbor distances, p(s), between ERES shows marked deviations from the assumption of randomly and independently positioned spots (Eqn 1; dashed line) in untreated (A) and CHX-treated (B) cells. In particular, small and large distances are suppressed, in agreement with the predictions of the model. Insets show representative fluorescence images of transfected CHO cells.