Fig. 6. Select restoration of dystrophin associated proteins by sarcolemmal
-dystrobrevin. (A,B) Palmitoylated
-dystrobrevin expressed on the sarcolemma of TA muscle of mdx mice restored the levels of
-syntrophin and AQP4 but failed to restore sarcolemmal nNOS as determined by (A) immunofluorescence and (B) immunoblots of membrane proteins. Sarcolemmal utrophin expression was not altered by sarcolemmal
-dystrobrevin. Data was obtained from TgDB-RPS lines 29 and 71. Scale bar, 50 µm.