Fig. 5. β-Dystroglycan and sarcoglycan expression in mdx mice expressing sarcolemmal
-dystrobrevin. (A,B) Palmitoylated
-dystrobrevin is specifically localized to the sarcolemma when expressed in the mdx mouse. However, the sarcolemmal
-dystrobrevin fails to restore normal levels of either β-dystroglycan or
-sarcoglycan, as determined by (A) immunofluorescence of TA muscle or (B) immunoblots of membrane proteins. Data were obtained from TgDB-RPS line 29. Scale bar, 50 µm.