Fig. 4. Transgenic
-dystrobrevin expression in the mdx mouse. (A) H&E stained tibialis anterior (TA) muscle shows that the dystrophic phenotype persists in the mdx mice, despite the expression of either transgenic
-dystrobrevin. (B) The number of centrally nucleated fibers in TA (dark shade), soleus (medium shade) and diaphragm (light shade) muscles are not significantly reduced by expression of either
-dystrobrevin transgene. (C) Serum creatine kinase levels in mdx mice with or without transgenic
-dystrobrevin are also similar. Error bars give ± s.d. Data was obtained from TgDB-RPS lines 29 and 71. Scale bar, 50 µm.