Fig. 5. Development of a DTC migration gene network. Red nodes represent the genes required for DTC migration isolated in this screen. Green nodes are a subset of interacting genes derived from a genome-wide prediction of C. elegans genetic and physical interactions (Zhong and Sternberg, 2006). For brevity, only red nodes are identified. For identities of all nodes see Fig. S1 in supplementary material. Identities of red nodes: (1) Y71G12B.11, (2) pat-3, (3) unc-112, (4) vab-10, (5) gex-3, (6) ced-5, (7) ced-10, (8) erm-1, (9) ina-1, (10) sdn-1, (11) gon-1, (12) unc-73, (13) dyn-1, (14) mig-15, (15) act-1, (16) unc-32, (17) cdc-42, (18) vab-3, (19) C16C10.6, (20) uba-2, (21) let-2, (22) rab-8, (23) cbp-1, (24) F32D1.2, (25) rpl-11.1, (26) ppn-1, (27) arf-3, (28) cogc-4, (29) apc-2, (30) ruvb-1, (31) cct-1, (32) W03H9.4, (33) F26F4.11, (34) cogc-3, (35) R53.6, (36) mcm-7, (37) icd-1, (38) Y65B4BR.5, (39) Y55F3AR.3, (40) tba-1, (41) mix-1, (42) smc-4, (43) tba-2, (44) tba-4, (45) ZK430.7, (46) H06I04.3, (47) F21C3.5, (48) snr-5, (49) T13H5.4, (50) Y59A8B.6, (51) F11A3.2, (52) tbg-1, (53) tbb-2, (54) imb-5, (55) tbb-1, (56) T04A8.3, (57) npp-9, (58) W07E6.1, (59) npp-10.