JCS -- Bradley et al. 116 (21): 4291 Figure IG5

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 4. cADPR did not increase the amplitude of depolarization-evoked Ca²⁺ transients. Depolarization (–70 to 0 mV, Aii,Bii,Cii) evoked Ca²⁺ transients; their amplitudes (expressed in F/F₀ units) were not significantly affected by cADPR ( ${downarrow}$ ; 50 µM, Ai, Bi, Ci) at various time intervals (A, 2 seconds; B, 5 seconds; C, 10 seconds) beforehand; that is, cADPR did not cause CICR following Ca²⁺ influx.