Fig. 1. Deficient epithelial tissue formation of HaCaT cells in organotypic
co-cultures. Epidermal tissue morphology of organotypic co-cultures of normal
keratinocytes (NEK) or HaCaT cells grown on collagen type I gels containing
2x105/ml postmitotic fibroblasts throughout a 12-day-culture
period (H and E staining; same magnification in all panels; bar, 100
µm).