Fig. 9. AIP1 reduces PYK-2 and FAK phosphotyrosine levels. HEK293 cells were transfected with lacZ or AIP1 proteins as indicated, and the endogenous PYK-2 or FAK proteins were immunoprecipitated. Western blots of the immunoprecipitates demonstrate similar levels of focal adhesion kinase proteins, but different levels of phosphotyrosine when AIP1 or, to a lesser extent, AIP1-784Stop are co-transfected.