Fig. 6. Effect of CD105 antisense ODN on cell apoptosis. Three groups of cells, AS- or SC-ODN-treated or untreated HDMECs, were exposed to hypoxia and/or TGF-ß1 for 24 hours, TUNEL-stained and analysed by FACS. The fluorescence intensity (A) and percentage of apoptotic cells (B) were determined. The apoptotic effect of TGFß1 was observed to be concentration dependent, with the maximal effect of TGFß1 at 10 ng/ml. Data were expressed as means±s.e.m. collected from six samples of three experiments. (*P<0.05 and **P<0.01, one-way ANOVA followed by the Duncan test).