Fig. 5. Recruitment of telomeric chromosome regions to the centromeric pole of the nucleus due to tetO-mediated centromeretelomere association. The positions of centromeres and telomeres of chromosomes V were highlighted by site-specific FISH probes (probes 1 and 2, see Fig. 1C) in different colours, and the SPB (marking the centromeric pole) by simultaneous immunostaining (see Fig. 2F,G). Distances of signals to the SPB were measured and given as a percent of the nuclear diameter.