Fig. 2. Mitosis in a neuroblast. During prophase (A) the nucleoplasm becomes granulated as the chromosomes condense. After NEB (B) the chromosomes attach to the forming spindle and quickly congress to a metaphase configuration (C). Metaphase chromosomes show little motion, and long chromosome arms are often aligned parallel to the spindle long axis (arrowheads). Sister chromatids disjoin synchronously at anaphase (D), and at this time the spindle also begins to elongate. Restitution nuclei form after the chromosomes reach the poles (F), and the spindle becomes asymmetrically positioned within the cell near the onset of telophase. Once this occurs the centrally located centrosome stops moving but spindle elongation continues by movement of the cortical centrosome (F-H). Cytokinesis is initiated during telophase (arrows in G) and progresses to form a midbody that separates the GMC from the neuroblast (arrow in H). Time is in minutes and seconds. Bar, 10 µm.