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Fig. 5. Ultrastructure of dermal capillaries in the skin of transgenic (B) and control (A) mice. The plasma membrane of endothelial cells (e) appears thinner and more irregular in transgenic mice compared with wild-type littermates. Several fenestrae (C, arrows) and gaps (D, arrowhead) are visible in the plasma membrane of transgenic mouse endothelial cells. p, pericyte. Bars, 1 µm.