Fig. 2. CrkRS is ubiquitously expressed and encoded by a single gene. (A) Multiple human tissue northern blots were probed with either the 3'UTR or the kinase domain of CrkRS. Two transcripts, of 6.8 kb and 8.5 kb in length, were recognised in all tissues tested with both probes. RNA size markers are indicated on the left. (B). Southern blot of human genomic DNA probed with the CrkRS 3'UTR probe. Each lane contained 10 µg of DNA digested, individually, with the restriction enzyme indicated. DNA size markers (kb) are indicated on the left.