
Fig. 6. SCP3 localization during the transition from pachytene to dictyate arrest. (A,D,G) CREST localization at the centromeres (red), (B,E,H) SCP3 (green) and (C,F,I) merged images. (A-C) Pachytene stage oocyte with SCP3 localization along the length of the SC. (D-F) Diplotene/early dictyate oocyte showing clustering of centromeres in regions of the nucleus and SCP3 localization at most but not all centromeres. (G-I) Late diplotene/dictyate cell exhibiting clustering of centromeres but no SCP3 staining above background levels. (Note: the temporal localization pattern of SCP2 is similar; see text for details.)